I've tried several of the suggestions listed here: toothpaste didn't work, campho phenique didn't work, potato slices didn't work. The only thing that worked, once, was applying aloe vera pulp, covering it overnight. That time, it opened in about 16 hours. Currently, I have one on my leg, going on almost a week. I've tried all of the things I already listed. I think it hasn't been ready to open, thus, it hasn't. So, I just did the aloe vera thing again, except this time, I sprinkled turmeric all over the aloe, then covered it with a non-absorbing gauze so the aloe will be absorbed by my skin and not the bandages. If anyone has any suggestions or advice as to what I may be doing wrong, I'd love to hear it. I'll try just about anything to avoid going to the ER. Thanks and if any progress, I'll post an update!
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