I get a cold sore about once every six months and I've tried it all. I have a method that gets rid of it in about 4 days. As soon as you feel the first sign, take a Q-tip or swab with nail polish remover on it and hold it on the sore for a minute or so until you feel it burn. Do this every 20 minutes to hour for the first 24 hours. Once the swelling is completely gone start to apply Neosporin as often as you can. You can also put Neosporin on in the first 24 hours while you are using the nail polish remover. It works better than any over the counter or prescription has.
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