I am 53 and have had restless leg syndrome (RLS) all my life. It does not disturb my sleep and any discomfort is minimal. I would automatically shake my legs during the day when the discomfort arose. For me I do not believe diet or exercise is a factor. I have found no such combination to help. Besides RLS I would say I am in excellent health. I only found out their was a name for my discomfort about 5 years ago. Since I always had this problem it was just part of my life. During the evening the discomfort would be worse, but moving my legs would make it better. I would often sleep without a pillow as that relieved the discomfort but it was not always necessary. As time went on the problem appears to be worse but still something I could live with since my sleep was not disturbed in anyway. I live outside the U.S. and while visiting a doctor I told him of my problem and without any testing he gave me dihydroergotoxine, 4.5 mg per day. I was not expecting any good results from this, but within a day or two I did not have the sensation to move my legs during the day hours at all. Late in the evening when I am on the coach or desk I would feel a little discomfort but much less than before. I would say this drug improved my situation by 90% and I have been on it for 9 months. I did some reading on this drug after being given the prescription and there was not much regarding its use for RLS, but there was on study that helped where the participants received 10 to 40mg. I noticed when I took a higher dose of up to 12mg there was no improvement for me. So the 4.5 mg is working fine. Now that I am so close to being 100 percent better I may look for some other options to get there, but I can't really complain and such a solution is now not a priority. Here is what one study said: open pilot study with the dopamine agonist alpha-dihydroergocryptine (DHEC) was conducted in 16 patients with idiopathic restless legs syndrome (RLS) over a period of 5 weeks. Following a drug-free interval of 1 week, the patients were treated with daily doses of 10 to 40 mg DHEC. As compared to baseline values, treatment led to a statistically significant reduction of subjective RLS symptoms. Overall complaints at night decreased significantly by 63.9 +/- 38.1% as measured by a visual analogue scale. Detailed evaluation of sensory discomfort, motor restlessness, involuntary movements, as well as sleep quality also showed significant improvement. Side effects were mostly mild and affected mainly the gastrointestinal tract. Five patients needed domperidone for treatment of concomitant nausea. One patient stopped the study due to nausea. In conclusion, the results of this open study suggest a role for DHEC in the treatment of RLS. Hopes this helps someone.
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