Per a research study from 2009, 74% percent of the participants had greatly reduced, or even -0- recurring canker sores after taking 1000 mcg of vitamin B-12 each night. I've had recurrent canker sores for years. Over time they increased in frequency and duration in all parts of my mouth. It was rare for me to have periods of time with no canker sores. I recently started taking B-12 and it seems to be very effective for me.
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