1 Comment for the Lungs Home Remedy
Fri, 07 Nov 2003 17:47:18 GMT
Drink comfrey or funugreek tea to relieve and relax the lungs.
Tue, 27 Dec 2005 15:20:58 GMT
To: American Botanical Council,
American Herbal Products Association,
Council for Responsible Nutrition,
Consumer Healthcare Products Association,
National Nutritional Foods Association,
Utah Natural Products Alliance,
American Association of Oriental Medicine, and the
American College of Acupuncturists and Traditional Medicine.
The Food and Drug Administration (FDA) is issuing this letter to communicate to you our concern about the marketing of dietary supplements that contain the herbal ingredient comfrey (Symphytum officionale (common comfrey), S. asperum (prickley comfrey), and S. x uplandicum (Russian comfrey). These plants are a source of pyrrolizidine alkaloids that present a serious health hazard to consumers when they are ingested. FDA asks that you share this information with your members.
The use of comfrey in dietary supplements is a serious concern to FDA. These plants contain pyrrolizidine alkaloids, substances which are firmly established to be hepatotoxins in animals. Reports in the scientific literature clearly associate oral exposure of comfrey and pyrrolizidine alkaloids with the occurrence of veno-occlusive disease (VOD) in animals. Moreover, outbreaks of hepatic VOD have been reported in other countries over the years and the toxicity of these substances in humans is generally accepted. The use of products containing comfrey has also been implicated in serious adverse incidents over the years in the United States and elsewhere. However, while information is generally lacking to establish a cause-effect relationship between comfrey ingestion and observed adverse effects humans, the adverse effects that have been seen are entirely consistent with the known effects of comfrey ingestion that have been described in the scientific literature. The pyrrolizidine alkaloids that are present in comfrey, in addition to being potent hepatotoxins, have also been shown to be toxic to other tissues as well. There is also evidence that implicates these substances as carcinogens. Taken together, the clear evidence of an association between oral exposure to pyrrolizidine alkaloids and serious adverse health effects and the lack of any valid scientific data that would enable the agency to determine whether there is an exposure, if any, that would present no harm to consumers, indicates that this substance should not be used as an ingredient in dietary supplements.
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